Pregnancy Exercise Increase Enzymatic Antioxidant In Pregnant Women

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Wagey Freddy Wagey

Keywords

oxidative stress, superoxide dismutase, gluthation peroxidase, catalase

Abstract

Objectives: Pregnancy is a vulnerable condition to all kinds of "stress", resulting in changes of physiological and
metabolic functions. This research aims to determine effect of exercise during pregnancy in increasing enzymatic
antioxidant marked by increase of superoxide dismutase (SOD), gluthation peroxidase (GSHPx), and catalase (CAT)
levels.
Methods: Randomized pre and posttest control group design was employed in this study. A number of 66 pregnant
women were recruited in this study and grouped into two groups, i.e 30 of them as control group and the rest as
treatment group. Pregnancy exercise was performed to all 36 pregnant women from 20 weeks gestation on treatment
group. The exercise was performed in the morning for about 30 minutes, twice a weeks. On the other hand, daily
activities was sugested for control group. Student’s t-test was then applied to determine the mean different of
treatment and control group with 5 % of significant value.
Results: This study reveals that there were significantly higher increase of (superoxide dismutase (SOD), gluthation
peroxidase (GSHPx), and catalse (CAT) levels of treatment group compare to control group. These enzymatic
antioxidant increase among these two group were around 1.36 g/gHb for SOD; 1.14 IU/gHb for GSHPx; and 0.97
IU/gHb for CAT, (p < 0.05). Clinical outcomes, such as strengten of pelvic muscle and quality of life of treatment
group were significantly better compared to control group (p < 0.05).
Conclusions: This means that exercise during pregnancy ages of 20 weeks increase enzymatic antioxidant levels
SOD, GSHPx, and CAT higher compare to control group without exercise.

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